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Pharmaceutical Raw Materials

Algae Calcium Carbonate Powder

Caltron is the leading manufacturer of Algae Calcium Powder or Algae Calcium Carbonate in India. Caltron has developed this specific grade with intention of competing globally with the best available calcium sources in the world.
The Algae Calcium Carbonate Powder is manufactured using good quality algae plants. The manufacturing procedure is checked at various stage of production including raw material sourcing till complete manufacturing and dispatching of products. The product offered by us is checked on various authentication parameters before final delivery.

The algae calcium is mild green in color and possess various plant nutrients such as magnesium, crude protein and carbohydrates.

The Algae Calcium Carbonate Powder is used in:
  • Algae calcium powder for neutraceuticals
  • Algae calcium powder for pharmaceutical formulation
  • Algae calcium powder for Dietary supplements
  • Algae calcium powder for Veterinary feed supplements
  • Algae calcium powder for Ayurvedic medicines
  • Algae calcium powder as an herbal extract.

Owing to our 2 decades of knowledge and expertise in pharma field we have developed this Algae Calcium Powder.

Features:
  • It is naturally derived yet vegetarian ( Approved by VEGAN AUTHORITY )
  • It is highly fibrous and helps in the proper absorption of calcium in the body.
  • The algae calcium is bio available in body for maximum absorption and is not like other synthetic calcium sources which results in stones.
  • Along with calcium it possess other plant nutrients such as carbohydrates, magnesium and crude protein for better efficiency.
Algae Calcium Carbonate Powder

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MCHC POWDER

MCHC POWDER
MCHC POWDER is a complex biological calcium salt manufactured under process designed to ensure that the components retain the natural form and physiological proportions. Caltron's MCHC is the only nutritional substance, which is clinically proven to stop bone loss and even restore lost bone density and helps relieve pain accompanying Osteoporosis. Caltron's MCHC Powder is composed of an organic mineral protein; collagen and the inorganic mineral hydroxyapatite together with broad range of trace minerals.

The Microcrystaline structure of Caltron's MCHC Powder, contributes to improved Calcium Absorption as it provides a large surface area from which the mineral in the organic metrics can be released in the intestine.

Molecular Formula of MCHC : 3Ca3(PO4)2 Ca(OH)2
Collagen : Around 30% of bone is composed of organic mineral, which 90-95% is collagen and the rest being non-collageous protein. Collagen is a fibrous protein, which provides bone strength and flexibility.

Hydroxy Apatite : Caltron's MCHC Powder contains more that 50% Hydroxy Apatite. Hydroxy apatite is a combination of Calcium and Phosphorus bound together in a physiological ratio 2:1 in a special matrix structure. X-ray diffraction studies have confirmed the presence of Hydroxy apatite and the micro-crystalline nature of the salt.

Product : 37126
Hydroxylapatite,for analysis


Product Details :
ColorWhite
Physical StatePowder
Molecular Formula3Ca3(PO4)2 Ca(OH)2
CAS No1306-06-05
Molecular Weight502.31
Loss on IgnitionLess than or equals to 8 % (800 deg C)


General Product Data
Version 0
CAS No 1306-06-5
Molecular weight 502.31
Molecular formula H Ca5 O13 P3
Linear formula 3Ca3(PO4)2.Ca(OH)2


Product Specifications :
Appearance white powder
Assay 35 to 40 % (Ca)
Loss on ignition =<8 % (800°C)
Heavy metals (as Pb) =<10 ppm
Insolubles in H2O =<0.2 % (in HCl)
Chloride(Cl) =<1500 ppm
Sulfate(SO4) =<5000 ppm
Iron (Fe) =<400 ppm
Fluoride(F) =<50 ppm
Copper (Cu) =<20 ppm
Zinc (Zn) =<20 ppm
Lead (Pb) =<5 ppm
Arsenic (As) =<2 ppm
Mercury (Hg) =<1 ppm
MCHC POWDER

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Diatom Powder Food Grade

Caltron’s Diatomaceous Earth (DE) powder Food Grade addresses a broad spectrum of harmful toxins entering the body including:

Diatom Powder Food Grade:
  • Bacteria
  • Parasities
  • Fungi
  • Protozoa
  • Viruses (including poliovirus)
  • Endotoxins
  • Pesticide and drug residues
  • E-Coli
  • Heavy Metals (including methyl mercury)
  • Proteinaceous toxins produced by some intestinal infections

Many harmful things entering the body have a positive charge. Silica is a semi-conductive mineral which when warmed by body heat becomes negatively charged and gives off electrons. These negatively charged mineral ions and/or individual shells attract bad microbes, free radicals, positively charged waste and other harmful things. Acting as magnets, the negatively charged shells and/or ions attract and absorb positive things that are small enough to go through the holes. Add a sugar molecule and you can trap toxins into the porous food-grade DE particle which is then excreted safely out of the body. Because of the strong charge, each shell can absorb a large number of positively charged substances, whether they be chemical or in the form of bacteria or viruses. They pass on through the stomach and intestine, taking these harmful substances out of the body.

The intake of silica through DE can help you in many ways:
  • Lower High Blood Pressure
  • Lower Cholestrol Level
  • Sore joints feeling better
  • Healthier skin
  • Hair That Grows
  • Teeth and Gums
  • Toughens nails


Specifications

Packaging Size 1 kg
Packaging Type Bottle
Color Off-White, Pale Yellow
Material Diaotm Powder
Grade Food Grade
Diatom Powder Food Grade

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HPMCP

Hydroxypropyl Methylcellulose Phthalate
HPMC Phthalate (PASS-55)
Caltron has pioneered the technology of manufacturing Hydroxypropyl Methylcellulose Phthalate or HPMCP in India. The material is manufactured under stringent quality standards. Our esteemed clients can avail high quality of Hydroxypropyl Methylcellulose Phthalate (PASS- 55) from us at market competitive prices. These are widely used for coating different types of granules, pellets, tablets and capsules. Moreover, these products are extensively used for binders and micro capsule bases. Moreover, The Hypromellose Phthalate (PASS-55) can be solely used as well as can also be used in combination with other polymers.

Applications:
Hydroxypropyl Methylcellulose Phthalate (PASS-55) is utilized in enteric film sustained time or a delayed release. In addition to being an excipient for enteric coating of tablets, HPMC-P also possesses (since recent past) biocidal properties, which helps in monitoring and controlling HIV-1 and similar viruses and STDs.

Hypromellose Phthalate Also Known as HPMCP or HydroxyPropyl MethylCellulose Phthalate or Cellulose, 2-Hydroxypropyl methylether, phthalic acid ester. Chemical CAS 9050-31-1.

Physical form:
Powder/Flakes

Properties:
"HPMCP" (hydroxypropyl methylcellulose phthalate), an enteric coating. It is widely used as an enteric coating agent by the pharmaceutical industry. "HPMCP"

It can dissolve at pH 5-5.5 and be controlled by varying the phthalyl content. We manufacture (PASS-55). A suitable grade of "HPMCP" for a particular purpose should be selected in accordance with the properties and formulations. (PASS-55) is applicable as a general enteric coating agent.

Applications:
  • Film coating of tablets
  • Enteric coating of tablets
  • Sustained release
  • Delayed release
  • Pallate coating material

Advantages of film coating :
  • Enhance palatability by masking unpleasant tastes or objectionable odours
  • Ease ingestion/swallowing
  • Improve product appearance
  • Protect tablets from light, oxidation & moisture
  • Advance the perception of superior product efficacy

TESTS RESULTS LIMITS
Description White powder with granules White powder or granules odorless And tasteless.
Solubility Insoluble in water, in dehydrated Alcohol, and in hexane. Products A viscous solution in a mixture of Methanol and dichloromethane (1:1) or in a mixture of dehydrated alcohol and acetone (1:1) Dissolves in 1N Sodium Hydroxide. Practically insoluble in water, in dehydrated alcohol, and in hexane. Products a viscous solution in a mixture of methanol and dichloromethane(1:1), or in a mixture of dehydrated alcohol and acetone (1:1)Dissolves in 1N Sodium hydroxide.
Identification IR absorption IR spectrum of sample concordants with that of Hydroxypropyl Methyl Cellulose Phthalate Working reference standard. IR spectrum of sample should be concordants with that of Hydroxypropyl Methly Cellulose phthalate Working reference standard.
Viscosity 46.8 CPS (115%) NLT 80% and NMT 120% of that indicted by the table (32-48 CPS)
Water 1.80 % NMT 5.00%
Residue on ignition 0.05% NMT 0.200%
Chloride LT 0.07% NMT 0.07%
Heavy Metals LT 0.001% NMT 0.001%
Free Phthalic Acid 0.7 % NMT 1.00%
Phthalyl Content 32.3% 27.00% - 35.00%
Organic Volatile impurite
A) Benzene
B )Chloroform
C )1,4 Dioxane
D )Methylene Chloride
E )Trichloroethylene
This Material are not Used in Process NMT 2 ppm
NMT 60 ppm
NMT 380 ppm
NMT 600 ppm
NMT 80 ppm
Cas No. 9050-31-1  
PH 5 - 5.5  
HPMCP

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CAP

“CALTO-CAP” Cellulose Acetate Phthalate
The Cellulose Acetate Phthalate (CALTO-CAP) is a cellulose derivative which is extensively used to coat tablets, pellets, granules and capsules. After being used as an enteric coating agent, in recent times, it is widely used for applications such as binders and micro capsule bases. This derivative provides excellent coating on different types of drugs.

The drug is also known as CAP or Cellacefate or Cellacephate or Cellulose Acetate 1,2 - Benzene Dicarboxylate. Chemical CA 9004-38-0
Physical form :
Powder/Flakes.

Properties :
CAP withstands itself in acidic media in stomach. But it readily dissolves in slight alkaline medium of small intestine.

Applications :
  • Film coating of tablets, granules, pellets or capsules
  • Enteric coating of tablets
  • Sustained release
  • Delayed release
  • Pallate coating material
  • C-A-P besides being excipients for enteric coating of tablets are also known (since recent past) to have biocidal properties.

Advantages of film coating:
  • Enhance palatability by masking unpleasant tastes or objectionable odours
  • Ease ingestion/swallowing
  • Improve product appearance
  • Protect tablets from light, oxidation & moisture
  • Advance the perception of superior product efficacy


Product Specifications
Description White free flowing powder
Solubility Passes
Identification A) B) C) Passes
Viscosity 72 CP (Limit btn 50 CP to 90 CP)
Free Acid 1-76 % (Limit max 3 %)
Sulphated 0.06 % (Limit max 0.1%)
Loss on Drying @ 015c 3.7 % (Limit max 5 %)
Assay as Acetyl Groups 22.4 % (Limit max 17 % - 26 %)
Phthalyl Groups 3.2 % (Limit max 30 % - 40 %)
CAP

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Calcium Carbonate DC grade

Calcium Carbonate Dc grade (Directly Compressible): - Caltron’s Calcium Carbonate DC Grade is manufactured at their state of the art manufacturing facility having all the latest machineries in place. The DC grade has got high purity of CaCO3 99% and above. The material is manufactured under stringent quality controls to make it fit for pharmaceutical industries. Our DC grade reduces time of production and is much more convenient and is produced as per the customer’s requirement.

CHEMICAL ANALYSIS OF CALCIUM CARBONATE GRANULES.

Chemical Analysis OBSERVATION LIMIT
DESCRIPTION White Granules White to Off White Granules
HEAVY METALS < 5 ppm 5 – 10 ppm
IRON < 300 ppm 0 – 300 ppm
BARIUM COMPLIES 0 – 20 ppm
CHLORIDE Negligible NMT 330 ppm
SULPHATE Traces 0 – 0.25%
LOSS ON DRYING (At 200 C) 1.48 % 1 – 2 %
TAPPED DENSITY 1.01 mg/ml 0.9 – 1.1
ASSAY 99.7 % 98.5 – 100.5
FLUORIDE Negligible 0 – 20 ppm
PARTICLE SIZE 31.9% retained on 20 mesh sieve
  67.2% retained on 30 mesh sieve
  80.8% retained on 60 mesh sieve
  91.3% retained on 200 mesh sieve

Our DC grade is available for Oyster Shell Calcium Carbonate, Precipitated Calcium Carbonate, Coral Calcium Carbonate, Calcite(Animal Feed) etc.
Calcium Carbonate DC grade

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Natural Calcium Carbonate

We are the leading manufacturer of Natural Calcium Carbonate. We are offering high-quality products to our clients.

Technical Specifications :

  • State : Powder, Liquid, Crystal
  • Packaging Type : Drum/Barrel
  • Grade Standard : Technical, Chemical & Industrial Grade
  • Molecular Formula : CaCO3
  • Color : White

 

Natural Calcium Carbonate

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